• Medical Degree – 2016 – Medical University of Varna, Bulgaria
• Postgraduate Training: Certification in Liver Elastography (Fibroscan – Echosens, 2024)

Significant research activity with a focus on hepatocellular carcinoma, systemic therapy and prognostic outcome markers. Participation in multicenter studies and development of prognostic survival models in patients with advanced HCC undergoing immunotherapy.

• Development of a novel prognostic score for 1-year survival in immunotherapy – treated patients with unresectable HCC: the ALIVE-IO score
• Reference: Frontiers of Immunology
• Authors: Spyridon Pantzios 1, Orestis Sidiropoulos 1, Antonia Syriha 1 , Nikolaos Ptohis 2, Ioannis Skouras 3, Evgenia Mainta3 , Dimitris P. Korkolis4, Nikolaos Machairas 5, Georgios Sotiropoulos5 and Ioannis Elefsiniotis 1
• Impact of neutrophil-to-lymphocyte ratio on survival outcomes among cirrhotic and non-cirrhotic patients with advanced hepatocellular carcinoma under natezolizumab-bevacizumab combination therapy
• Reference: Annals of Gastroenterology
• Authors: Spyridon Pantzios, Orestis Sidiropoulos, Antonia Syriha, Ioanna Stathopoulou, Sofia Rellou, Emmanouil Nychas, Georgia Barla, Nikolaos Ptohis, Ioannis Elefsiniotis.
• Efficacy of atezolizumab-bevacizumab combination therapy early after recurrence of hepatocellular carcinoma following resection or ablation with a curative intent
• Authors: Spyridon Pantzios, Antonia Syriha, Ioanna Stathopoulou, Orestis Sidiropoulos, Sofia Rellou, Georgia Barla, Nikolaos Ptohis, Dimitris P. Korkolis, Georgios C. Sotiropoulos, Ioannis Elefsiniotis | Journal Name: Annals of Gastroenterology Endoscopic retrograde cholangiopancreatography training conditions, results from a pan-European survey: Between vision and reality
• Journal Name: UEG Journal Evaluation of gastroenterology training curriculum in Greece Alexandros Ioannou, Konstantina Dimopoulou, Evripidis Rizos, Eleni Manthopoulou, Oresti Sidiropoulos, Evgenia Papathanasiou, Georgios Tziatzios, Konstantina Paraskeva, Ioannis S. Papanikolaou
• Reference: United European Gastroenterology Journal DOI: 10.1002/ueg2.12630

3rd place award at the Panhellenic Gastroenterology Conference (2022) for work related to small bowel enteroscopy.

•  Secretary General of the Board of the Professional Association of Gastroenterologists of Greece (EPEGE)
• Former President of the Residency Section of the Hellenic Gastroenterological Society
• Member of the Hellenic Society for the Study of the Liver (HASL) – Website Committee
• Journal Reviewer at Frontiers of Immunology
• Journal Reviewer at Frontiers of Oncology
• Journal Reviewer at Annals of Gastroenterology

Active participation with presentations (poster and oral) in numerous Greek and international conferences, including leading events such as EASL, AASLD and Digestive Disease Week (DDW).

• Numerous scientific publications in international journals such as Annals of Gastroenterology, UEG Journal and Frontiers in Immunology, as well as numerous announcements at Greek and international conferences
• Numerous scientific papers published in foreign and Greek medical journals
• Numerous papers at international and Greek scientific conferences